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F-MELT® F1

F-MELT® F1 is a premium-quality co-spray dried pre-mix excipient specially designed for the manufacturing of dietary supplements, nutraceuticals, and pharmaceuticals.

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Product Overview

F-MELT® F1 is a white to pale yellow powder excipient from Fuji Chemical designed for the production of patient-centric drug delivery systems for the delivery of medications. Its easy direct compressibility and rapid disintegration in less than 30 seconds are optimal for oral disintegrating tablets (ODTs) and chewable tablets without the risk of bitter flavor. Upon use, it imparts excellent tablet hardness and API loading of more than 50% to pharmaceuticals, dietary supplements, and nutraceutical formulations. 

Specifications

Appearance: White to pale yellow powder
Loose bulk density (g/ml): 0.50
Mean particle size distribution (μm): 139
Angle of repose (°): 31
Loss on drying (%), (105°C, 4hr ): 5.9
Ingredients: Waxy rice starch, Microcrystalline Cellulose, Dibasic Calcium Phosphate Anhydrous (DCPA)
CAS Numbers: 9005-25-8, 9004-34-6, 7757-93-9
 

Features & Benefits

Ready-to-use excipient
Directly compressible
Rapid disintegration
Excellent flowability
Provides high API loading
High tablet hardness capabilities
No special ODT equipment necessary
No royalty or license fees required
Non-GMO
Allergen free

Applications

Nutraceutical excipient
Dietary supplements
Food applications
 

Problems Solved

Poor tablet hardness for orally disintegrating tablet drugs
Slow disintegration of ingredients in ODT drugs
Bitter taste of traditional ODTs 
Difficulty swallowing alternative drug delivery systems      
 

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